Overview
Muscular endurance—the ability of muscles to sustain force production or perform repeated contractions over an extended period without a significant decline in performance—is a fundamental component of athletic performance in many sports. It is limited by both central factors, such as neural fatigue, and peripheral factors, including metabolic fatigue within the muscles.
At a peripheral level, muscular endurance depends heavily on adequate oxygenation. Aerobic energy production, which is considerably more efficient than anaerobic metabolism, requires a continuous supply of oxygen to the muscle cells. When oxygenation is insufficient, the muscles rely more heavily on anaerobic glycolysis, leading to faster lactate accumulation and the earlier onset of fatigue.
Characteristics
Muscular endurance is not determined by training alone. It is also significantly influenced by microcirculation and the vascular supply to muscle tissue. Athletes with inadequate microcirculation in active muscles may experience a faster decline in performance during prolonged exercise, even when their overall physical condition is good.
Chronic intensive endurance training is also associated with the cumulative development of muscle-fibre micro-injuries and metabolic fatigue. Without adequate recovery, these factors may reduce muscular endurance.
Muscle fibres that do not recover fully between training sessions accumulate tissue injury over time, leading to a persistent reduction in endurance and an increased risk of injury.

Scientific Basis
Research involving endurance athletes has examined the relationship between hyperbaric oxygen therapy and muscular endurance. Findings have indicated improvements in markers of aerobic capacity, including mitochondrial activity and vascular density within the muscles, following the systematic use of hyperbaric oxygen therapy.
Studies have also reported faster lactate clearance and lower levels of muscle-injury markers following intensive exercise in athletes who received hyperbaric oxygen therapy. These findings suggest faster metabolic recovery and an improved ability to perform repeated bouts of intensive exercise.
The Role of Hyperbaric Oxygen Therapy
In programmes intended to improve muscular endurance, hyperbaric oxygen therapy may be incorporated as an adjunctive intervention that supports the adaptations produced by endurance training itself. It does not replace training, but may optimize the biological environment in which these adaptations occur.
The increased availability of oxygen under hyperbaric conditions stimulates mitochondrial biogenesis—the production of new mitochondria, the structures responsible for aerobic energy production within muscle cells.
At the same time, the stimulation of neovascularisation improves vascular density within the muscles, allowing a more effective oxygen supply during prolonged exercise.
Treatment is usually administered during an endurance-training period in courses of 15 to 25 sessions, in collaboration with the sports medicine physician and endurance coach.